Pregnancy-associated Cancers: A Narrative Review

Authors

  • Giovanna Esposito Department of Clinical Sciences and Community Health, University of Milan https://orcid.org/0000-0001-7894-4456
  • Carlo La Vecchia Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy https://orcid.org/0000-0003-1441-897X
  • Francesco Fedele Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy; Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan https://orcid.org/0000-0002-8202-748X
  • Fabio Parazzini Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy https://orcid.org/0000-0001-5624-4854

DOI:

https://doi.org/10.54103/2282-0930/22286

Keywords:

cancer, chemotherapy, pregnancy

Abstract

Pregnancy-associated cancers are malignancies diagnosed during pregnancy or within one year of delivery or abortion. These cancers present unique challenges because of the delicate balance required for maternal-fetal health. Diagnosis can be made complex by physiological changes associated with pregnancy, and treatment decisions must take into account potential harm to the foetus. Multidisciplinary collaboration between oncologists and obstetricians is essential. Despite the complexities, early detection and tailored management can optimise outcomes for both mother and child. A systematic approach is currently lacking; further research into prenatal exposure to maternal cancer is recommended to formulate evidence-based guidelines for the management of cancer in pregnancy.

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Published

2024-02-16

Issue

Section

Narrative Reviews
Received 2024-01-11
Accepted 2024-01-23
Published 2024-02-16