More Days, Greater Health: Associations Between Daily MVPA and Cardiometabolic Risk in Youth
DOI:
https://doi.org/10.54103/2282-0930/28449Keywords:
moderate-to-vigorous physical activity, cardiometabolic healthAbstract
Objectives: To examine the associations of moderate-to-vigorous intensity physical activity (MVPA) with cardiometabolic health risks in children and adolescents. We also investigated the differences in MVPA between boys and girls and how the differences in MVPA affect cardiometabolic health.
Methods: Pooled data from 21 studies involving children and adolescents aged 3-18 years old from the International Children's Accelerometry Database (ICAD). MVPA was measured objectively by accelerometry. A Clustered Cardio-Metabolic Risk Score (CCMR) was calculated based on central adiposity, blood pressure, lipid profile, and glucose metabolism indicators.
Results: Boys are more active than girls per week in the study. In regression analysis, the MVPA-adjusted models for the fasting blood sample group indicated that CCMR in category 6 was significantly lower than in category 3(t = 2.41, p < .05). The results are similar in the non-fasting blood sample group.
Conclusions: MVPA is associated with cardiometabolic health. More MVPA is beneficial for cardiometabolic health in children and adolescents.
Downloads
References
[1] P. Rao, M. J. Belanger, and J. M. Robbins, ‘Exercise, Physical Activity, and Cardiometabolic Health: Insights into the Prevention and Treatment of Cardiometabolic Diseases’, Cardiology in Review, vol. 30, no. 4, pp. 167–178, Jul. 2022, doi: 10.1097/CRD.0000000000000416.
[2] S. Mubarik et al., ‘Epidemiology and demographic patterns of cardiovascular diseases and neoplasms deaths in Western Europe: a 1990–2019 analysis’, Public Health, vol. 231, pp. 187–197, Jun. 2024, doi: 10.1016/j.puhe.2024.04.003. DOI: https://doi.org/10.1016/j.puhe.2024.04.003
[3] B. Vogel et al., ‘The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030’, The Lancet, vol. 397, no. 10292, pp. 2385–2438, Jun. 2021, doi: 10.1016/S0140-6736(21)00684-X. DOI: https://doi.org/10.1016/S0140-6736(21)00684-X
[4] W. M. Schultz et al., ‘Socioeconomic Status and Cardiovascular Outcomes: Challenges and Interventions’, Circulation, vol. 137, no. 20, pp. 2166–2178, May 2018, doi: 10.1161/CIRCULATIONAHA.117.029652. DOI: https://doi.org/10.1161/CIRCULATIONAHA.117.029652
[5] C. J. Lavie, C. Ozemek, S. Carbone, P. T. Katzmarzyk, and S. N. Blair, ‘Sedentary Behavior, Exercise, and Cardiovascular Health’, Circulation Research, vol. 124, no. 5, pp. 799–815, Mar. 2019, doi: 10.1161/CIRCRESAHA.118.312669. DOI: https://doi.org/10.1161/CIRCRESAHA.118.312669
[6] P. Rao, M. J. Belanger, and J. M. Robbins, ‘Exercise, Physical Activity, and Cardiometabolic Health: Insights into the Prevention and Treatment of Cardiometabolic Diseases’, Cardiology in Review, vol. 30, no. 4, pp. 167–178, Jul. 2022, doi: 10.1097/CRD.0000000000000416. DOI: https://doi.org/10.1097/CRD.0000000000000416
[7] H. C. McGill et al., ‘Obesity Accelerates the Progression of Coronary Atherosclerosis in Young Men’, Circulation, vol. 105, no. 23, pp. 2712–2718, Jun. 2002, doi: 10.1161/01.CIR.0000018121.67607.CE. DOI: https://doi.org/10.1161/01.CIR.0000018121.67607.CE
[8] S. M. Grundy, ‘Obesity, Metabolic Syndrome, and Coronary Atherosclerosis’, Circulation, vol. 105, no. 23, pp. 2696–2698, Jun. 2002, doi: 10.1161/01.CIR.0000020650.86137.84. DOI: https://doi.org/10.1161/01.CIR.0000020650.86137.84
[9] R. H. Eckel and R. M. Krauss, ‘American Heart Association Call to Action: Obesity as a Major Risk Factor for Coronary Heart Disease’, Circulation, vol. 97, no. 21, pp. 2099–2100, Jun. 1998, doi: 10.1161/01.CIR.97.21.2099. DOI: https://doi.org/10.1161/01.CIR.97.21.2099
[10] E. B. Rimm et al., ‘Body Size and Fat Distribution as Predictors of Coronary Heart Disease among Middle-aged and Older US Men’, American Journal of Epidemiology, vol. 141, no. 12, pp. 1117–1127, Jun. 1995, doi: 10.1093/oxfordjournals.aje.a117385. DOI: https://doi.org/10.1093/oxfordjournals.aje.a117385
[11] Q. Liu et al., ‘Beneficial effects of moderate to vigorous physical activity on cardiovascular disease among Chinese adults’.
[12] F. C. Bull et al., ‘World Health Organization 2020 guidelines on physical activity and sedentary behaviour’, Br J Sports Med, vol. 54, no. 24, pp. 1451–1462, Dec. 2020, doi: 10.1136/bjsports-2020-102955. DOI: https://doi.org/10.1136/bjsports-2020-102955
[13] J.-P. Chaput et al., ‘2020 WHO guidelines on physical activity and sedentary behaviour for children and adolescents aged 5–17 years: summary of the evidence’, Int J Behav Nutr Phys Act, vol. 17, no. 1, p. 141, Dec. 2020, doi: 10.1186/s12966-020-01037-z. DOI: https://doi.org/10.1186/s12966-020-01037-z
[14] M. S. Tremblay et al., ‘Canadian 24-Hour Movement Guidelines for Children and Youth: An Integration of Physical Activity, Sedentary Behaviour, and Sleep’, Appl. Physiol. Nutr. Metab., vol. 41, no. 6 (Suppl. 3), pp. S311–S327, Jun. 2016, doi: 10.1139/apnm-2016-0151. DOI: https://doi.org/10.1139/apnm-2016-0203
[15] S. G. Trost, ‘State of the Art Reviews: Measurement of Physical Activity in Children and Adolescents’, American Journal of Lifestyle Medicine, vol. 1, no. 4, pp. 299–314, Jul. 2007, doi: 10.1177/1559827607301686. DOI: https://doi.org/10.1177/1559827607301686
[16] L. Hamari et al., ‘Physical activity among children: objective measurements using Fitbit One® and ActiGraph’, BMC Res Notes, vol. 10, no. 1, p. 161, Dec. 2017, doi: 10.1186/s13104-017-2476-1. DOI: https://doi.org/10.1186/s13104-017-2476-1
[17] P. C. Hallal, L. B. Andersen, F. C. Bull, R. Guthold, W. Haskell, and U. Ekelund, ‘Global physical activity levels: surveillance progress, pitfalls, and prospects’, The Lancet, vol. 380, no. 9838, pp. 247–257, Jul. 2012, doi: 10.1016/S0140-6736(12)60646-1. DOI: https://doi.org/10.1016/S0140-6736(12)60646-1
[18] S. G. Trost et al., ‘Age and gender differences in objectively measured physical activity in youth’:, Medicine and Science in Sports and Exercise, vol. 34, no. 2, pp. 350–355, Feb. 2002, doi: 10.1097/00005768-200202000-00025. DOI: https://doi.org/10.1097/00005768-200202000-00025
[19] R. M. Telford, R. D. Telford, L. S. Olive, T. Cochrane, and R. Davey, ‘Why Are Girls Less Physically Active than Boys? Findings from the LOOK Longitudinal Study’, PLoS ONE, vol. 11, no. 3, p. e0150041, Mar. 2016, doi: 10.1371/journal.pone.0150041. DOI: https://doi.org/10.1371/journal.pone.0150041
[20] G. S. Berenson, S. R. Srinivasan, W. Bao, W. P. Newman, R. E. Tracy, and W. A. Wattigney, ‘Association between Multiple Cardiovascular Risk Factors and Atherosclerosis in Children and Young Adults’, N Engl J Med, vol. 338, no. 23, pp. 1650–1656, Jun. 1998, doi: 10.1056/NEJM199806043382302. DOI: https://doi.org/10.1056/NEJM199806043382302
[21] H. C. McGill et al., ‘Association of Coronary Heart Disease Risk Factors With Microscopic Qualities of Coronary Atherosclerosis in Youth’, Circulation, vol. 102, no. 4, pp. 374–379, Jul. 2000, doi: 10.1161/01.CIR.102.4.374. DOI: https://doi.org/10.1161/01.CIR.102.4.374
[22] D. R. Jacobs et al., ‘Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events’, N Engl J Med, vol. 386, no. 20, pp. 1877–1888, May 2022, doi: 10.1056/NEJMoa2109191. DOI: https://doi.org/10.1056/NEJMoa2109191
[23] N. Salamt, M. Muhajir, A. Aminuddin, and A. Ugusman, ‘The effects of exercise on vascular markers and C-reactive protein among obese children and adolescents: An evidence-based review’, Bosn J of Basic Med Sci, Sep. 2019, doi: 10.17305/bjbms.2019.4345. DOI: https://doi.org/10.17305/bjbms.2019.4345
[24] K. Watts, T. W. Jones, E. A. Davis, and D. Green, ‘Exercise Training in Obese Children and Adolescents’, 2005. DOI: https://doi.org/10.2165/00007256-200535050-00002
[25] A.-M. Parrish et al., ‘Comparing and assessing physical activity guidelines for children and adolescents: a systematic literature review and analysis’, Int J Behav Nutr Phys Act, vol. 17, no. 1, p. 16, Dec. 2020, doi: 10.1186/s12966-020-0914-2. DOI: https://doi.org/10.1186/s12966-020-0914-2
[26] L. DiPietro et al., ‘Advancing the global physical activity agenda: recommendations for future research by the 2020 WHO physical activity and sedentary behavior guidelines development group’, Int J Behav Nutr Phys Act, vol. 17, no. 1, p. 143, Dec. 2020, doi: 10.1186/s12966-020-01042-2. DOI: https://doi.org/10.1186/s12966-020-01042-2
[27] L. M. Schumacher, J. G. Thomas, R. R. Wing, H. A. Raynor, R. E. Rhodes, and D. S. Bond, ‘Sustaining Regular Exercise During Weight Loss Maintenance: The Role of Consistent Exercise Timing’, Journal of Physical Activity and Health, vol. 18, no. 10, pp. 1253–1260, Oct. 2021, doi: 10.1123/jpah.2021-0135. DOI: https://doi.org/10.1123/jpah.2021-0135
[28] N. Ferrari and C. Joisten, ‘Impact of physical activity on course and outcome of pregnancy from pre- to postnatal’, Eur J Clin Nutr, vol. 75, no. 12, pp. 1698–1709, Dec. 2021, doi: 10.1038/s41430-021-00904-7. DOI: https://doi.org/10.1038/s41430-021-00904-7
[29] G. D. Batty, M. J. Shipley, M. Marmot, and G. Davey Smith, ‘Physical activity and cause‐specific mortality in men with Type 2 diabetes/impaired glucose tolerance: evidence from the Whitehall study’, Diabetic Medicine, vol. 19, no. 7, pp. 580–588, Jul. 2002, doi: 10.1046/j.1464-5491.2002.00748.x. DOI: https://doi.org/10.1046/j.1464-5491.2002.00748.x
[30] M. Imierska, A. Kurianiuk, and A. Błachnio-Zabielska, ‘The Influence of Physical Activity on the Bioactive Lipids Metabolism in Obesity-Induced Muscle Insulin Resistance’, Biomolecules, vol. 10, no. 12, p. 1665, Dec. 2020, doi: 10.3390/biom10121665. DOI: https://doi.org/10.3390/biom10121665
[31] S. R. Colberg et al., ‘Exercise and Type 2 Diabetes’, Diabetes Care, vol. 33, no. 12, pp. e147–e167, Dec. 2010, doi: 10.2337/dc10-9990. DOI: https://doi.org/10.2337/dc10-9990
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Jianhong Han, Hyo Lee, Damien Vitiello

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Funding data
-
Chinese Government Scholarship
Grant numbers 202108510062
Accepted 2025-04-30
Published 2025-09-11


