Psychopathology and hormonal disturbances in eating disorders

Authors

  • Pierpaola D’Arista Department of Psychiatry, University Hospital “A. Gemelli”, Rome, Italy
  • Pamela Blanco Department of Psychiatry, University Hospital “A. Gemelli”, Rome, Italy
  • Mariangela Rutilo Department of Psychiatry, University Hospital “A. Gemelli”, Rome, Italy
  • Alice Mannocci Unit of Epidemiology and Biostatistics, Institute of Hygiene, Rome, Italy
  • Giuseppe La Torre Unit of Epidemiology and Biostatistics, Institute of Hygiene, Rome, Italy
  • Antonio Ciocca Department of Psychiatry, University Hospital “A. Gemelli”, Rome, Italy
  • Pietro Bria Department of Psychiatry, University Hospital “A. Gemelli”, Rome, Italy

DOI:

https://doi.org/10.2427/5825

Keywords:

Eating disorders, hormonal disturbances, neuropsychological functions

Abstract

Background: Our aim was to study the relationship between hormonal disturbances and psychopathology in Eating Disorders (ED).

Methods: Forty-nine women diagnosed as Eating Disorders according to DSM-IV were subjected to control plasma levels of TSH, FT3, FT4, LH, FSH, 17beta-estradiol, prolactin, cortisol, DHEAS, GH and IGF-1. They were also administered by SCL-90R, BAT, DES II questionnaires. We applied multivariate regression models.

Results: Our results highlight a statistically significant relation between LH, FSH and prolactin decreased levels, mood and thought disturbances (subscales 3, 5, 7, 8 and 9 of SCL-90r) which are associated to Body Attitude ( BAT total scale) and Dissociative Experiences (DES II total scale).

Conclusions: Decreased sexual hormones levels could have a role in ED psychological disturbances, not inquired yet.

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Published

2024-04-19

Issue

Vol. 5 No. 3 (2008)

Section

Theme Papers