The grassblade beyond Newton: the pragmatizing of Kant for evolutionary-developmental biology

  • Lenny Moss
  • Stuart A. Newman

Abstract

Much of the philosophical attention directed to Kant’s intervention into biology has been directed toward Kant’s idea of a transcendental limit upon what can be understood constitutively.  Kant’s own wider philosophical practice, however, was principally oriented toward solving problems and the scientific benefits of his methodology of teleology have been largely underappreciated, at least in the English language literature.  This paper suggests that all basic biology has had, and continues to have, a need for some form of heuristic “bracketing” and that a renewal of some form of, albeit flexible, teleological methodological bracketing can better complement the productive assimilation into developmental biology of continuing advances in our understanding of the mesoscale physics and chemistry of soft, excitable condensed matter, than what has been the prevailing and de facto use of a form of bracketing shaped by the neoDarwinian Modern Synthesis.  Further we offer a concept of biogeneric processes and a framework of physico-genetic “dynamical patterning modules”, that can begin to account for the appearance of new Kantian “stocks of Keime und Anlagen”, capable of potentiating some range of possible organismal forms, and provide grounds for moving up the teleological “goalposts”, i.e., expanding the range of what can be accounted for on a constitutive basis. 

Riferimenti bibliografici

BRODLAND, G. Wayne, The differential interfacial tension hypothesis (DITH): a comprehensive theory for the self-rearrangement of embryonic cells and tissues, in «J Biomech Eng.» 124 (2002), pp. 188-197;

CANEVA, Kenneth, Teleology with regrets, «Annals of Science» 47 (1990), pp. 291–300.

CARROLL, Sean B., Endless forms most beautiful: the new science of evo devo and the making of the animal kingdom, New York, W.W. Norton & Co., 2005.

CHARLESWORTH, Brian, Evolution: on the origins of novelty and variation (Review of The plausibility of life: resolving Darwin's dilemma by KIRSCHNER, Marc W. and GERHART, John C.), in «Science» 310 (2005), pp. 1619-1620.

CONWAY MORRIS, Simon, Darwin's dilemma: the realities of the Cambrian 'explosion', «Philos Trans R Soc Lond B Biol Sci.» 361 (2006), pp. 1069-1083.

COOKE, John, ZEEMAN, Erik Christopher, A clock and wavefront model for control of the number of repeated structures during animal morphogenesis, «J Theor Biol.» 58 (1976), pp. 455-476.

DEPEW, Daniel J., WEBER, Bruce H., Darwinism evolving: systems dynamics and the genealogy of natural selection, Cambridge MA, MIT Press, 1995.

DROSER, Mary L., GEHLING, James G., Synchronous aggregate growth in an abundant new Ediacaran tubular organism, «Science» 319 (2008), pp. 1660-1662.

FORGACS, Gabor, NEWMAN, Stuart A., Biological physics of the developing embryo, Cambridge, Cambridge University Press, 2005.

FRIEDMAN, Michael, Kant and the exact sciences, Cambridge MA, Harvard University Press, 1992.

GLIMM, Tilmann, BHAT, Ramray, NEWMAN, Stuart A., Modeling the morphodynamic galectin patterning network of the developing avian limb skeleton, «J Theor Biol.» 346 (2014), pp. 86-108;

GOMEZ, Céline, POURQUIÉ, Olivier, Developmental control of segment numbers in vertebrates, «Journal of Experimental Zoology Part B» 312B (2009), 6, pp. 533-544.

KANT, Immanuel, Critique of the power of judgment, ed. by P. Guyer, Cambridge, Cambridge University Press, 2000.

KANT, Immanuel, On the use of teleological principles in philosophy, in Anthropology, history and education, Cambridge, Cambridge University Press, 2007.

KRIEG, Michel, ARBOLEDA-ESTUDILLO, Yohanna, PUECH, Pierre-Henri, KAFER, Jos, GRANER, François, MULLER, Daniel J., HEISENBERG, Carl-Philipp, Tensile forces govern germ-layer organization in zebrafish, in «Nat Cell Biol.» 10 (2008), pp. 429-436.

LARROUX, Claire, LUKE, Graham L., KOOPMAN, Peter, ROKHSAR, Daniel S., SHIMELD, Sebastian M., DEGNAN, Bernard M., Genesis and expansion of metazoan transcription factor gene classes, «Mol Biol Evol.» 25 (2008), pp. 980-996;

LENOIR, Timothy, The strategy of life: teleology and mechanics in nineteenth century German biology, Dordrecht, Holland - Boston, U.S.A., D. Reidel Pub. Co., 1982.

LENOIR, Timothy, The strategy of life: teleology and mechanics in nineteenth century German biology, Dordrecht (Holland) – Boston (U.S.A.), D. Reidel Pub. Co., 1982, p. 160.

LEWIS, Julian, Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator, «Curr Biol.» 13 (2003), pp. 1398-1408;

MAYR, Ernst, The growth of biological thought: diversity, evolution, and inheritance, Cambridge MA, Belknap Press, 1982.

MONK, Nicholas A., Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays, «Curr Biol.» 13 (2003), pp. 1409-1413.

MOSS, Lenny, What genes can't do, Cambridge MA, MIT Press, 2003.

NEWMAN, Stuart A., BHAT, Ramray, Dynamical patterning modules: a "pattern language" for development and evolution of multicellular form, «Int J Dev Biol.» 53 (2009), pp. 693-705.

NEWMAN, Stuart A., BHAT, Ramray, Dynamical patterning modules: physico-genetic determinants of morphological development and evolution, «Phys. Biol.» 5 (2008), 15008;

NEWMAN, Stuart A., BHAT, Ramray, Lamarck's dangerous idea, in GISSIS, Snait, JABLONKA, Eva (eds.), Transformations of Lamarckism: from subtle fluids to molecular biology, Cambridge MA, MIT Press, 2011, pp. 157-169.

NEWMAN, Stuart A., BHAT, Ramray, MEZENTSEVA, Nadejda V., Cell state switching factors and dynamical patterning modules: complementary mediators of plasticity in development and evolution, «J Biosci.» 34 (2009), pp. 553-572.

NEWMAN, Stuart A., H.L. Frisch, Dynamics of skeletal pattern formation in developing chick limb, «Science» 205 (1979), pp. 662-668.

NEWMAN, Stuart A., LINDE-MEDINA, Marta, Physical determinants in the emergence and inheritance of multicellular form, «Biological Theory» 8 (2013), pp. 274-285.

NEWMAN, Stuart A., Physico-genetics of morphogenesis: the hybrid nature of developmental mechanisms, in A. Minelli, T. Pradeu (eds.), Towards a theory of development, Oxford, Oxford University Press, 2014, pp. 95-113.

NEWMAN, Stuart A., Physico-genetics of morphogenesis: the hybrid nature of developmental mechanisms, in MINELLI, Alessandro, PRADEU, Thomas (eds.), Towards a theory of development, Oxford, Oxford University Press, 2014, pp. 95-113.

NEWMAN, Stuart A., William Bateson's physicalist ideas, in M. Laubichler, J. Maienschein (eds.), From embryology to Evo-Devo: a history of evolutionary development, Cambridge MA, MIT Press, 2007, pp. 83-107.

ORBÁN, Miklos P., DE KEPPER, Patrick, EPSTEIN, Irving R., An iodine-free chlorite-based oscillator. The chlorite-thiosulfate reaction in a continuous flow stirred tank reactor, «J. Phys. Chem. A.» 86 (1982), pp. 431-433.

PALMEIRIM, Jorge, HENRIQUE, Domingos, ISH-HOROWICZ, David, POURQUIÉ, Olivier, Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis, «Cell.» 91 (1997), pp. 639-648.

RASPOPOVIC, Jelena, MARCON, Luciano, RUSSO, Laura, SHARPE, James, Modeling digits. Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients, «Science» 345 (2014), pp. 566-570.

RICHARDS, Robert J., Kant and Blumenbach on the Bildungstrieb: A Historical Misunderstanding, «Stud. Hist. Phil. Biol. & Biomed. Sci.» 31 (2000), pp. 11–32.

ROKAS, Antonis, KRUGER, Dirk, CARROLL, Sean B., Animal evolution and the molecular signature of radiations compressed in time, «Science» 310 (2005), pp. 1933-1938.

SHEN, Binghui, DONG, Li, XIAO, Shuhao, KOWALEWSKI, Michael, The Avalon explosion: evolution of Ediacara morphospace, «Science» 319 (2008), pp. 81-84.

SLOAN, Phillip, Buffon, German biology, and the historical interpretation of biological species, «British J. Hist. Sci.» 12 (1979), pp. 109–153.

STEINBERG, Malcolm S., Goal-directedness in embryonic development, «Integrative Biology» 1 (1998), pp. 49-59.

STEINBERG, Malcolm S., On the mechanism of tissue reconstruction by dissociated cells, I. Population kinetics, differential adhesiveness, and the absence of directed migration, «Zool.» 48 (1962), pp. 1577-1582.

STEINBERG, Malcolm S., On the mechanism of tissue reconstruction by dissociated cells, III. Free energy relations and the reorganization of fused, heteronomic tissue fragments, «Proc. Natl. Acad. Sci. USA.» 48 (1962), pp. 1769-1776.

TURING, Alan M., The chemical basis of morphogenesis, «Phil. Trans. Roy. Soc. Lond. B.» 237 (1952), pp. 37-72.

WADDINGTON, Conrad Hal, Canalization of development and the inheritance of acquired characters, «Nature» 150 (1942), pp. 563-565.

WATKINS, Eric, Kant and the metaphysics of causality, Cambridge, Cambridge University Press, 2005.

WEBSTER, Gerry, GOODWIN, Brian C., Form and transformation: generative and relational principles in biology, Cambridge-New York, Cambridge University Press, 1996.

WINKLBAUER. Rudolf, Cadherin function during Xenopus gastrulation, «Subcell Biochem» 60 (2012), pp. 301-320.

YIN, Lei, ZHU, Maoyan, KNOLL, A. Hans, YUAN, Xiaochen, ZHANG, Jianzhi, HU, Jianping, Doushantuo embryos preserved inside diapause egg cysts, «Nature» 446 (2007), pp. 661-663.

ZAMMITO, John H., The Lenoir thesis revisited: Blumenbach and Kant, «Stud. His. Phil. Biol. Biomed. Sci» 43 (2012), pp. 120-132.

ZHU, Jun, ZHANG, Yong-Tao, ALBER, Mark S., NEWMAN, Stuart A., Bare bones pattern formation: a core regulatory network in varying geometries reproduces major features of vertebrate limb development and evolution, «PLoS One.» 5 (2010), e10892.

Pubblicato
2016-01-01
Fascicolo
Sezione
Focus - Assessing Well-Being: Aesthetic and Political Atmospheres